232 research outputs found
Fundamentals of interface phenomena in advanced bulk nanoscale materials
The review is devoted to a study of interface phenomena influencing advanced properties of nanoscale materials processed by means of severe plastic deformation, high-energy ball milling and their combinations. Interface phenomena include processes of interface defect structure relaxation from a highly nonequilibrium state to an equilibrium condition, grain boundary phase transformations and enhanced grain boundary and triple junction diffusivity. On the basis of an experimental investigation, a theoretical description of the key interfacial phenomena controlling the functional properties of advanced bulk nanoscale materials has been conducted. An interface defect structure investigation has been performed by TEM, high-resolution x-ray diffraction, atomic simulation and modeling. The problem of a transition from highly non-equilibrium state to an equilibrium one, which seems to be responsible for low thermostability of nanoscale materials, was studied. Also enhanced grain boundary diffusivity is addressed. Structure recovery and dislocation emission from grain boundaries in nanocrystalline materials have been investigated by analytical methods and modeling
Investigation of the Exclusive 3He(e,e'pp)n Reaction
Cross sections for the 3He(e,e'pp)n reaction were measured over a wide range
of energy and three- momentum transfer. At a momentum transfer q=375 MeV/c,
data were taken at transferred energies omega ranging from 170 to 290 MeV. At
omega=220 MeV, measurements were performed at three q values (305, 375, and 445
MeV/c). The results are presented as a function of the neutron momentum in the
final-state, as a function of the energy and momentum transfer, and as a
function of the relative momentum of the two-proton system. The data at neutron
momenta below 100 MeV/c, obtained for two values of the momentum transfer at
omega=220 MeV, are well described by the results of continuum-Faddeev
calculations. These calculations indicate that the cross section in this domain
is dominated by direct two-proton emission induced by a one-body hadronic
current. Cross section distributions determined as a function of the relative
momentum of the two protons are fairly well reproduced by continuum-Faddeev
calculations based on various realistic nucleon-nucleon potential models. At
higher neutron momentum and at higher energy transfer, deviations between data
and calculations are observed that may be due to contributions of isobar
currents.Comment: 14 pages, 1 table, 17 figure
Knockout of proton-neutron pairs from O with electromagnetic probes
After recent improvements to the Pavia model of two-nucleon knockout from
O with electromagnetic probes the calculated cross sections are compared
to experimental data from such reactions. Comparison with data from a
measurement of the O(e,epn) reaction show much better agreement
between experiment and theory than was previously observed. In a comparison
with recent data from a measurement of the O(,pn) reaction the
model over-predicts the measured cross section at low missing momentum.Comment: 6 pages, 5 figure
First measurements of the ^16O(e,e'pn)^14N reaction
This paper reports on the first measurement of the ^16O(e,e'pn)^14N reaction.
Data were measured in kinematics centred on a super-parallel geometry at energy
and momentum transfers of 215 MeV and 316 MeV/c. The experimental resolution
was sufficient to distinguish groups of states in the residual nucleus but not
good enough to separate individual states. The data show a strong dependence on
missing momentum and this dependence appears to be different for two groups of
states in the residual nucleus. Theoretical calculations of the reaction using
the Pavia code do not reproduce the shape or the magnitude of the data.Comment: 10 pages, 11 figures, 2 tables, Accepted for publication in EPJ
Ground-state correlations and final state interactions in the process 3He(e,e'pp)n
The two-proton emission process is theoretically investigated
using realistic three-nucleon wave functions and taking the final state
interaction into account by an approach which can be used when the value of the
three-nucleon invariant mass is either below or above the pion emission
threshold. Various kinematical conditions which enhance or minimize the effects
of the final state interaction are thoroughly analyzed.Comment: 26 pages, 12 eps-figures. Introduction and abstract updated, few
references added and Apendix A remove
The He(e, ed)p Reaction in q-constant Kinematics
The cross section for the He(e, ed)p reaction has been measured as a
function of the missing momentum in q -constant kinematics at
beam energies of 370 and 576 MeV for values of the three-momentum transfer
of 412, 504 and 604 \mevc. The L(+TT), T and LT structure functions have been
separated for = 412 and 504 \mevc. The data are compared to three-body
Faddeev calculations, including meson-exchange currents (MEC), and to
calculations based on a covariant diagrammatic expansion. The influence of
final-state interactions and meson-exchange currents is discussed. The
-dependence of the data is reasonably well described by all calculations.
However, the most advanced Faddeev calculations, which employ the AV18
nucleon-nucleon interaction and include MEC, overestimate the measured cross
sections, especially the longitudinal part, and at the larger values of .
The diagrammatic approach gives a fair description of the cross section, but
under(over)estimates the longitudinal (transverse) structure function.Comment: 17 pages, 7 figure
A study of backward going and in interactions with the NOMAD detector
Backward proton and production has been studied in
interactions with carbon nuclei. Detailed analyses of the momentum
distributions, of the production rates, and of the general features of events
with a backward going particle, have been carried out in order to understand
the mechanism producing these particles. The backward proton data have been
compared with the predictions of the reinteraction and the short range
correlation models.Comment: 29 pages, 14 figures, submitted to Nucl. Phys.
HPV type concordance in sexual couples determines the effect of condoms on regression of flat penile lesions
We earlier demonstrated, in a randomised clinical trial, that the regression time of flat penile lsions in male sexual partners of women with cervical intraepithelial neoplasia (CIN) was shorter in men who used condoms compared to those who did not. To further evaluate this finding, we examined whether the effect of condom use on the regression of flat penile lesions depends on the presence of human papillomavirus (HPV) type concordance in sexual couples, as determined in cervical and penile scrapes by GP5+/6+ PCR testing. A Cox model with time-dependent covariates showed a beneficial effect of condoms on regression of flat penile lesions in concordant couples (hazard ratio 2.63, 95% CI 1.07–6.48) but not in those who were nonconcordant. When both partners harboured different HPV types, no effect of condoms was found (hazard ratio 0.90, 95% CI 0.27–2.96). Delayed regression of flat penile lesions was associated with either stable lesions or with new penile lesions developing at sites surrounding pre-existing lesions suggesting reinfection of the penile epithelium. We conclude that condom use blocks sexual HPV transmission by preventing reinfection and development of new penile lesions in men who are susceptible to the same type as present in the female partner
Multiple primary malignancies and subtle mucocutaneous lesions associated with a novel PTEN gene mutation in a patient with Cowden syndrome: Case report
<p>Abstract</p> <p>Background</p> <p>Cowden syndrome (CS) is a cancer predisposition syndrome associated with increased risk of breast, thyroid, and endometrial cancers, and is characterized by development of benign mucocutaneous lesions.</p> <p>Case presentation</p> <p>Here we report on a 58-year-old woman with multiple primary malignancies and subtle mucocutaneous lesions such as small polyps and wart-like papulas. Over a period of 23 years, she developed various malignant neoplasms including thyroid, ovarian, stomach, and colon carcinomas, and a benign meningioma. Direct sequencing analysis of the <it>PTEN </it>gene revealed a novel germline mutation (c.438delT, p.Leu146X).</p> <p>Conclusion</p> <p>This case demonstrates that Cowden syndrome is a multi-system disease that can result in the development of multiple malignant and benign tumors.</p
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